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EBOVAC Laboratory Manager (Sierra Leone)
Job Title: EBOVAC Laboratory Manager (Sierra Leone)
Location: Sierra Leone
Company: London School of Hygiene & Tropical Medicine
Job Summary: Seeking to appoint a Laboratory Manager to the LSHTM EBOVAC team to be based in Sierra Leone.
Job Description: We are seeking to appoint a Laboratory Manager to the LSHTM EBOVAC team to be based in Sierra Leone. The Ebola vaccine projects – EBOVAC1, EBOVAC2 and EBODAC – are a series of trials and associated projects which aim to assess a novel prime-boost preventive vaccine regimen against Ebola Virus Disease (EVD). In a prime-boost vaccine regimen, individuals are first given a dose to prime the immune system, and then a boost dose which is intended to enhance the immune response and increase the duration of the response. The vaccine has been developed by Janssen Vaccines and Prevention B.V. and the trial is funded by the Innovative Medicines Initiative (IMI, a partnership between the EU and the European pharmaceutical industry). Between them, the EBOVAC1 andEBOVAC2 projects will assess – through several clinical trials conducted in phases in Europe and Africa – the safety, tolerability and immunogenicity of the vaccine regimen in response to the urgent public health need raised by the Ebola epidemic. One of the major trial sites for this work is in Sierra Leone. The post-holder will be based in Kambia district, northern Sierra Leone, with occasional travel to Freetown and will be an integral part of the management team supporting the implementation of the EBOVAC1 and EBOVAC3 vaccine studies. The laboratory has recently expanding to include new studies including a trial of different prophylactic Ebola vaccines and a new study, PREVAC-Up, will start later in 2019. The EBOVAC trial site in Kambia has dedicated laboratory facilities, currently staffed with two LSHTM lab scientists and 8 locally recruited lab technicians. In addition, the EBOVAC Laboratory Director is based in Kilifi, Kenya with regular travel to Kambia. The purpose of this Laboratory Manager position is to provide on the ground oversight of lab activities on a day-to-day basis, in order to support the work of the Laboratory Director and to ensure that this new laboratory meets the requirements of the trial sponsor and international standards. Key responsibilities include: supporting the Laboratory Director in the management of all laboratory activities managing LSHTM laboratory staff and locally-employed laboratory personnel ensuring all laboratory activities related to the EBOVAC programme and ancillary and future studies are performed in strict accordance to Good Clinical Laboratory Practice (GCLP) ensuring that the laboratory maintains a robust training programme being the local focal laboratory contact for trial sponsors, in-country partners and senior LSHTM management organising and facilitating laboratory meetings and attending EBOVAC1/3 and related meetings assisting with communications, including production of laboratory update reports.
Requirements: The successful applicant will have a higher degree or equivalent professional experience, significant experience of managing an accredited clinical diagnostic laboratory that undertakes clinical trials, practical experience and detailed understanding of implementing regulatory procedures and documentation relating to clinical trials, experience of promoting excellence in areas of laboratory administration and the provision of support services, including the setting of service standards and monitoring of performance, advising on laboratory matters at a senior level, experience of planning laboratory activities for new projects, including budgets, staffing, infrastructure, facilities and equipment. Further particulars are included in the job description.
How to apply: Please apply: https://jobs.lshtm.ac.uk/vacancy.aspx?ref=ITD-CRD-2019-08
Closing Date: 07/05/2019
Additional information: This full-time post, based in Sierra Leone, is funded by the Innovative Medicines Initiative under the European Commission’s Horizon 2020 Framework Programme until 31 December 2020. Salary is on the Professional Support Grade 6 scale in the range £39,304-£44,634 per annum.
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